Nadeem Khan made his Test debut for Pakistan in the third Test against the West Indies at St. John's in May 1993. The 23-year-old left-arm spinner was thrown into the action immediately. In the first innings, Nadeem Khan bowled 38 overs, including 5 maidens, and conceded 147 runs, highlighting a long spell under the Caribbean sun. During this marathon spell, he secured the key wickets of Desmond Haynes and Brian Lara. Although match was ended in draw, but his performance was noted as he dismissed two key wickets of west indies batting line up. He is the brother of Pakistan Captain Moin Khan.